Also called: Despair, Hopelessness
Sense of despondency, hopelessness, loss of meaning in life.

Top Bible Verses about Depression

1 Kings 19:9–18

He came to the cave there and spent the night there. Suddenly the word of Yahweh came to him and asked him, “Elijah, what are you doing here?” Then he said, “I have been very zealous for Yahweh the God of hosts, for the Israelites have forsaken your covenant. They have demolished your altars, and they have killed your prophets with the sword. I alone am left over, and they seek to take my life. He said, “Go out and stand on the mountain before Yahweh.” Suddenly Yahweh was passing by, with a … Read 1 Kings 19:9–18

Psalm 42:1–11

As a deer longs for streams of water, so my soul longs for you, O God. My soul thirsts for God, for the living God. When shall I come and appear before God? My tears have been my food day and night, while they say to me all day long, “Where is your God?” These I remember and I pour out my soul within me: that I would go with the multitude; I led them in procession to the house of God, with a voice of rejoicing and thanksgiving, a crowd celebrating a festival. Why are you in despair, O my soul, … Read Psalm 42:1–11

Psalm 88:1–18

O Yahweh, God of my salvation, I cry out by day and through the night before you. Let my prayer come before you; incline your ear to my cry. For my soul is full with troubles, and my life approaches Sheol. I am reckoned with those descending to the pit. I am like a man without strength, set free among the dead, like the slain lying in the grave, whom you no longer remember, even those cut off from your hand. You have set me in the pit below, in dark places, in the depths. Your wrath presses upon … Read Psalm 88:1–18

Ecclesiastes 2:18–23

So I hated all my toil with which I have toiled under the sun, for I must leave it behind to someone who will be after me. And who knows whether he will be wise or foolish? Yet he will exercise control of all the fruit of my toil with which I toiled wisely under the sun. This also is vanity! So I began to despair of all the toil with which I toiled under the sun. For there is a person who toils with wisdom and knowledge and skill, but he must leave his reward to someone who has not toiled for … Read Ecclesiastes 2:18–23

Matthew 27:3–5

Then when Judas, the one who had betrayed him, saw that he had been condemned, he regretted what he had done and returned the thirty silver coins to the chief priests and elders, saying, “I have sinned by betraying innocent blood!” But they said, “What is that to us? You see to it!” And throwing the silver coins into the temple he departed. And he went away and hanged himself. Read Matthew 27:3–5

Famous Christian Quotes About Depression, Despair, Hopelessness

Chastisement Is an Unspeakable Mercy

It is an unspeakable mercy that the Father comes with His chastisement, makes the world round us all dark and unattractive, leads us to feel more deeply our sinfulness, and for a time lose our joy in what was becoming so dangerous. He does it in the hope that, when we have found our rest in Christ in time of trouble, we shall learn to choose abiding in Him as our only portion; and when the affliction is removed, have so grown more firmly into Him, that in prosperity He still shall be our only joy. So much has He set His heart on this, that though He has indeed no pleasure in afflicting us, He will not keep back even the most painful chastisement if He can but thereby guide His beloved child to come home and abide in the beloved Son.

Andrew Murray

Acedia, the Sorrow Without Reason

There is a useful sorrow, and a destructive sorrow. Sorrow is useful when we weep for sin, and for our neighbor’s ignorance, and so that we may not relax our purpose to attain to true goodness: these are the true kinds of sorrow. Our enemy adds something to this. For he sends sorrow without reason, which is something called acedia. We ought always to drive out a spirit like this with prayer and psalmody.

Syncletica of Alexandria

When the Grace of God Is Not Evident

When the grace of God comes to a man he can do all things, but when it leaves him he becomes poor and weak, abandoned, as it were, to affliction. Yet, in this condition he should not become dejected or despair. On the contrary, he should calmly await the will of God and bear whatever befalls him in praise of Jesus Christ, for after winter comes summer, after night, the day, and after the storm, a great calm.

Thomas à Kempis
Related Media
See more
Get this media plus thousands more when you start a free trial.
Get started for FREE
Related Sermons
See more

More Sermon Ideas

See all sermon themes →