1.The Plague of Blood Exodus 7:14-24 turning the Nile to blood, was a judgment against Apis, the god of the Nile, Isis, goddess of the Nile, and Khnum, guardian of the Nile. The Nile was also believed to be the bloodstream of Osiris, who was reborn each year when the river flooded. The river, which formed the basis of daily life and the national economy, was devastated, as millions of fish died in the river and the water was unusable. Pharaoh was told, “By this you will know that I am the LORD” (Exodus 7:17).
2.The Plague of Frogs – Exodus 8:1-15 from the Nile, was a judgment against Heqet, the frog-headed goddess of birth. Frogs were thought to be sacred and not to be killed. God had the frogs invade every part of the homes of the Egyptians, and when the frogs died, their stinking bodies were heaped up in offensive piles all through the land (Exodus 8:13–14).
3.The Plague of Gnats – Exodus 8:16-19 were a judgment on Set, the god of the desert. Unlike the previous plagues, the magicians were unable to duplicate this one and declared to Pharaoh, “This is the finger of God” (Exodus 8:19).
4.The Plague of Flies – Exodus 8:20-32 was a judgment on Uatchit, the fly god. In this plague, God clearly distinguished between the Israelites and the Egyptians, as no swarms of flies bothered the areas where the Israelites lived (Exodus 8:21–24).
5.The Plague on Livestock – Exodus 9:1-7 was a judgment on the goddess Hathor and the god Apis, who were both depicted as cattle. As with the previous plague, God protected His people from the plague, while the cattle of the Egyptians died. God was steadily destroying the economy of Egypt, while showing His ability to protect and provide for those who obeyed Him. Pharaoh even sent investigators (Exodus 9:7) to find out if the Israelites were suffering along with the Egyptians, but the result was a hardening of his heart against the Israelites.
6.The Plague of Boils – Exodus 9:8-12 was a judgment against several gods over health and disease (Sekhmet, Sunu, and Isis). This time, the Bible says that the magicians “could not stand before Moses because of the boils.” Clearly, these religious leaders were powerless against the God of Israel.
Before God sent the last three plagues, Pharaoh was given a special message from God. These plagues would be more severe than the others, and they were designed to convince Pharaoh and all the people “that there is none like me in all the earth” (Exodus 9:14). Pharaoh was even told that he was placed in his position by God, so that God could show His power and declare His name through all the earth (Exodus 9:16). As an example of His grace, God warned Pharaoh to gather whatever cattle and crops remained from the previous plagues and shelter them from the coming storm. Some of Pharaoh’s servants heeded the warning (Exodus 9:20), while others did not.